BEXIMCO PHARMACEUTICALS LTD.

NEWS RELEASE
28 June 2015

Beximco Pharma launches generic version of breakthrough Hepatitis C drug

 

Leading drug manufacturer Beximco Pharma today announces the launch of generic version of the wonder drug Sofosbuvir for treating Hepatitis C under the brand name ' Sofovir C'. Sofosbuvir is a revolutionary drug recently launched by Gilead Sciences Inc, under its brand Sovaldi which is considered to be the most effective medication to treat hepatitis C with a cure rate of 90%. This is available as tablet and devoid of side effects that are seen with existing injectable therapies. The breakthrough drug, however, costs $1,000 (Tk. 78,400) per tablet in the developed market making it one of the most expensive medicines in the world.

"Beximco Pharma is always committed to bringing new therapies and making them affordable to our patients. We are proud to have played a role in introducing this breakthrough therapy at a price which is currently the lowest in the world," Beximco Pharma Managing Director Mr. Nazmul Hassan said. Available at Tk. 600 (US$ 7.65) per tablet the total cost of therapy would be Tk. 50,400 (US$ 643) only for a 12-week course compared to that of whooping Tk. 6.6 million (US$ 84,000) in developed countries.

Globally, it is estimated that 170-185 million people (about 3 percent of the world’s population) are chronically infected with hepatitis C virus (HCV). Untreated chronic hepatitis C increases the risk of cirrhosis of liver, liver failure and hepatocellular carcinoma. In Bangladesh, Hepatitis C emerges as a major health problem with nearly two million patients estimated to be infected with the virus.

BEXIMCO PHARMACEUTICALS LTD.

 

Beximco Pharmaceuticals Ltd. (BPL) has rolled out a good number of products in January 2014, thanks to our R&D and Marketing team. This launching will meet the therapeutic gap needs across Endocrine Disorders,Corticosteroids, Antibiotics, Cardiovascular, Gastrointestinal, Anti-asthma, and Local anesthetic portfolios of BPL.

Endocrine Disorders

Femzole®

Letrozole 2.5 mg Tablet
Femzole® is the preparation of letrozole, an oral, anti-estrogen drug that is used for treating postmenopausal women with breast cancer. The growth of some breast cancers in postmenopausal women is promoted by estrogens that circulate in the blood, and the adrenal glands are the main source of these circulating estrogens. Letrozole inhibits the enzyme in the adrenal glands (aromatase) that produces the estrogens, estradiol and estrone.
Femzole® is indicated for:

  • Adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer
  • Extended adjuvant treatment of postmenopausal women with early breast cancer who have received prior standard adjuvant tamoxifen therapy
  • First and second-line treatment of postmenopausal women with hormone receptor positive or unknown advanced breast cancer.

Norestin®

Norethisterone 5 mg Tablet
Norestin® is the preparation of Norethisterone. Norethisterone is a molecule used in some combined oral contraceptive pills, progestogen only pills and is also available as a stand-alone drug. If contraceptive protection is required, additional non hormonal contraceptive methods should be used.
Norestin® is indicated for:

  • Spasmodic Dysmenorrhea
  • Management of perimenopausal symptoms
  • Premenstrual tension
  • Management of endometriosis
  • For Dysfunctional Uterine Bleeding
  • Prophylaxis against recurrent dysfunctional bleeding
  • For the treatment of inoperable cancer of the breast
  • For postponement of menstruation

Synroid®

Levothyroxine Sodium 50 mcg Tablet
Synroid® contains synthetic Levothyroxine Sodium which is identical to the natural hormone, produced in the thyroid gland. Thyroid hormones regulate multiple metabolic processes and play an essential role in normal growth and development, and normal maturation of the central nervous system and bone.
Synroid® indicated for the following conditions:

  • As replacement therapy in hypothyroidism of any etiology.
  • For the suppression of Thyroid Stimulating Hormone (TSH) levels in the presence of goiters, nodules and after radiological and/or surgical treatment of thyroid cancer.
  • For the suppression of the goitrogenic effects of other drugs such as lithium.
  • As a diagnostic aid in suppression tests.

 

Corticosteroids

Bexipred®

Prednisolone 20 mg Tablet
Prednisolone is a corticosteroid drug with predominant glucocorticoid & low mineralocorticoid activity.
Bexipred® is indicated for:

  • as an anti-inflammatory or immunosuppressive agent for certain allergic, dermatologic, gastrointestinal, hematologic, ophthalmologic, nervous system, renal, respiratory, rheumatologic, specific infectious diseases or conditions and organ transplantation
  • for the treatment of certain endocrine conditions
  • for palliation of certain neoplastic conditions ( Hematologic disorders: Idiopathic thrombocytopenic purpura in adults, secondary thrombocytopenia in adults, acquired (autoimmune) hemolytic anemia, eythroblastopenia (RBC anemia), congenital (erythroid) hypoplastic anemia.

Odeson®

Dexamethasone 5 mg Tablet
Dexamethasone is a synthetic corticosteroid exhibiting both anti-inflammatory and immuno- suppressant properties. Corticosteroids are hormones produced naturally by the adrenal glands which have many important functions on every organ system.
Odeson® is indicated for:

  • As an anti-inflammatory medication. Dexamethasone relieves inflammation in various parts of the body. It is used specifically to decrease swelling (edema), associated with tumors of the spine and brain, and to treat eye inflammation.
  • To treat or prevent allergic reactions.
  • As treatment of certain kinds of autoimmune diseases, skin conditions, asthma and other lung conditions.
  • As treatment for a variety of cancers, such as leukemia, lymphoma, and multiple myeloma.
  • To treat nausea and vomiting associated with some chemotherapy drugs.
  • Conditions of adrenal insufficiency (low production of needed steroids produced by the adrenal glands).

 

Antiemetic

Onsat 4& 8 Oral Soluble Film

Ondensetron 4 mg & 8mg
Onsat® (ondansetron) oral soluble film is the first orally dissolving film introduced by Beximco Pharmaceuticals Ltd. in Bangladesh. Onsat® offers an innovative and convenient, easy-to-take formulation for patients who have trouble swallowing tablets, while providing the trusted efficacy expected from ondansetron.
Onsat® OSF is designed to be applied on top of the tongue where it will dissolve within 20 seconds and then is swallowed with saliva. Onsat® does not require water to aid dissolution or swallowing.
The active ingredient in Onsat® is ondansetron base, the racemic form of ondansetron, and a selective blocking agent of the serotonin 5-HT3 receptor type.
Onsat® Oral Soluble Film is indicated for:

  • Prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy.
  • Prevention of nausea and vomiting associated with initial and repeat courses of moderately emetogenic cancer chemotherapy.
  • Prevention of nausea and vomiting associated with radiotherapy in patients receiving total body irradiation, single high-dose fraction to abdomen, or daily fractions to the abdomen.
  • Prevention of postoperative nausea and/or vomiting

 

Oral Antibiotics

Azithrocin® 250

Azithromycin 250 mg Tablet
Azithrocin® 250 is supplied for oral administration as film-coated tablets containing azithromycin dihydrate equivalent to 250 mg azithromycin. It is an azalide, a subclass of macrolide antibiotics, active against Gram-positive and gram-negative organisms. Azithromycin interferes with ribosome function in susceptible bacteria by inhibiting the translocation of peptide.
Azithrocin® (Azithromycin) is indicated for infections caused by susceptible organisms, in upper respiratory tract infections including sinusitis, pharyngitis and tonsillitis, in lower respiratory tract infections including bronchitis and pneumonia, skin and soft tissue infections, and otitis media. Azithrocin® is indicated for pelvic inflammatory disease. It is indicated in the treatment of uncomplicated genital infections due to Chlamydia trachomatis. It is a good addition in Azithrocin® family as the tablet can be taken regardless of meal making it an ideal choice for pediatric patients.

Clinacyn®

Clindamycin 150 & 300 mg Capsule
Clindamycin is a lincosamide antibiotic. Clindamycin inhibits bacterial protein synthesis by binding to the 50S subunit of the ribosome. It has activity against Gram-positive aerobes and anaerobes as well as the Gram-negative anaerobes.
Clindamycin is indicated in the treatment of serious infections caused by susceptible anaerobic bacteria. Clindamycin is also indicated in the treatment of serious infections due to susceptible strains of streptococci, pneumococci and staphylococci. Its use should be reserved for penicillin-allergic patients or other patients for whom, in the judgment of the physician, a penicillin is inappropriate.

 

Gastrointestinal

Frelax®

Magnesium Hydroxide and Liquid Paraffin Oral Emulsion
Frelax® Oral Emulsion is a combination of Magnesium Hydroxide and Liquid Paraffin which is recommended for the temporary relief of constipation. Magnesium Hydroxide has an indirect cathartic action, which results from water retention in the stomach lumen due to increased osmotic pressure. Liquid Paraffin acts as a mild laxative by softening stools thus easing defecation.
Frelax® Oral Emulsion is indicated for Constipation, Hyperacidity with constipation, Anorectal disorder, Post-operative constipation, Constipation associated with chronic cholecystitis, Hernia.

Digecid® Plus

Megaldrate 480 mg+ Simethicone 20 mg / 5ml suspension
Magaldrate/simethicone suspension is an antacid and antiflatulent combination. The antacid works by neutralizing stomach acid and increasing the pH of the stomach. The antiflatulent works by breaking up gas bubbles, which makes gas easier to eliminate.
Digecid® Plus is indicated to relieve symptoms of dyspepsia, heartburn, acid indigestion, sour stomach, gastroesophageal reflux and hiatal hernia. It is also prescribed in hyperacidity associated with peptic ulcers, gastritis and esophagitis. Also indicated for the relief of flatulence, abdominal distension and windy colic. Digecid® Plus suspension is specially formulated with high acid neutralizing capacity (ANC).

Viscocid®

Sodium Alginate 500 mg & Potassium Bicarbonate 100mg / 5ml suspension
Viscocid® is the combination of Sodium Alginate & Potassium Bicarbonate that relieves the symptoms of reflux such as heartburn. Sodium Alginate is a naturally occurring substance. It reacts with the acid in the stomach to form a gel. Potassium Bicarbonate also reacts with the acid in the stomach to form bubbles of carbon dioxide. These bubbles are trapped by the gel and they allow the gel to float like a raft on top of the stomach contents. The raft prevents acid in the stomach from flowing back into the food pipe.
Viscocid® suspension is indicated for the treatment of symptoms of gastro-oesophageal reflux such as acid regurgitation, heartburn and indigestion (related to reflux), for example, following meals or during pregnancy or in patients with symptoms related to reflux oesophagitis.

Opton®

Esomeprazole 20 & 40 mg Delayed Release Capsule
Opton® capsule is the line extension of Opton brand supplied in delayed-release capsules. Each delayed-release capsule contains 20 mg, or 40 mg of esomeprazole.
Opton® is a proton pump inhibitor indicated for:

  • Treatment of Gastroesophageal Reflux Disease (GERD)
  • Risk Reduction of NSAID-Associated Gastric Ulcer
  • H. pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence
  • Pathological Hypersecretory Conditions Including Zollinger-Ellison Syndrome.

 

Antihypertensive

Indelix SR®

Indepamide1.5 mg Sustained Release Tablet
Indelix® SR (Indepamide) is an oral antihypertensive which belongs to class of drug called diuretic. It is a prolonged-release film-coated tablet containing indapamide as the active ingredient.
Indelix® SR is indicated for the treatment of hypertension, alone or in combination with other antihypertensive drugs. It is also indicated for the treatment of salt and fluid retention associated with congestive heart failure.

 

Anti-asthma

Monocast® 4 Granules

Montelukast 4 mg granules/sachet
Monocast Granules sachet is a leukotriene receptor antagonist that blocks substances called leukotrienes. Leukotrienes causes narrowing and swelling of airways in the lungs. By blocking leukotrienes montelukast improves asthma symptoms and helps control asthma.
Monocast® 4 Granules is used for the treatment of 6 months to 5 year old patients who are not adequately controlled on their medication and need additional therapy. Monocat® Granules may also be used as an alternative treatment to inhaled corticosteroids for 2 to 5 year old patients who have not recently taken oral corticosteroids for their asthma and have shown that they are unable to use inhaled corticosteroids. It also helps prevent the narrowing of airways triggered by exercise for patients 2 years of age and older.

Mucomist®- DT

Acetylcysteine 600 mg dispersible Tablet
Mucomist® DT is the preparation of Acetylcysteine, a derivative of the amino acid, cysteine. Each dispersible tablet contains Acetylcysteine 600 mg. The dispersible tablet formulation ensures optimum stability, rapid dissolution, maximal absorption and high bioavailability. Acetylcysteine has a mucolytic activity through its free sulfhydryl group. It acts directly on the mucoproteins to open the disulfide bonds and thus lowers the viscosity of the mucous and facilitates its removal by the muco-cillary action and expectoration.
Mucomist® DT is indicated for the treatment of abnormal, sticky, or thick mucus secretions in various lung problems (eg, chronic emphysema, bronchitis, asthmatic bronchitis, pneumonia, during anesthesia, following surgery or various lung tests).
Mucomist® DT should be dissolved in 1/2 glass of water before use (preferably in the evening). The duration of treatment should be 5 to 10 days in the acute phase. It may be continued in the chronic state for up to 6 months or according to the advice of the physician.

Tioriva® Bexicap

Dry Powder Inhaler
Tiotropium Capsule
Tioriva® Bexicap capsule contains Tiotropium Bromide Monohydrate BP as the active ingredient which is a long-acting, antimuscarinic agent (LAMA), which is often referred to as an anticholinergic. The combipack is supplied with easy-to-operate Bexihaler device.
Tioriva® Bexicap is indicated for:

  • long-term, once-daily maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.

Breathlin® SR® Bexicap

Theophylline 200 mg sustained release Tablet
Theophylline is a bronchodilator, structurally classified as a Methylxanthine. Theophylline has a direct relaxant effect on the smooth muscle of bronchial airways and pulmonary blood vessels, serving as a bronchodilator and pulmonary vasodilator.
Breathlin® SR is indicated for:

  • The treatment of the symptoms and reversible airflow obstruction associated with chronic asthma and other chronic lung diseases, like emphysema and chronic bronchitis.

 

Anti-diabetic

Informet® LA 750

Metformin Hydrochloride 750 mg extended release Tablet
Metformin Hydrochloride belongs to a biguanide class of oral antidiabetic drugs. It decreases hepatic glucose production, decreases intestinal absorption of glucose and improves insulin sensitivity. Unlike sulfonylureas, Metformin Hydrochloride does not produce hypoglycemia. It is the drug of first choice in obese patients.
Informet® LA 750 is a long acting tablet formulation. The usual starting dose is 750 mg once daily with the evening meal. Dosage increase should be made in increments of 750 mg weekly, up to maximum of 1500 mg once daily with the evening meal after consulting with doctor.

 

Anti-dandruff

Resolve®

Ketoconazole BP 2% Therapeutic Shampoo
Resolve is the preparation of Ketoconazole 2% shampoo, a broad spectrum imidazole-dioxolane synthetic antifungal agent. It also contains Zinc pyrithione 1% as antiseborrheic and keratolytic agent and conditioner, glusol.
Resolve shampoo is indicated for:

  • to control dandruff. It helps to relieve the flaking, scaling and itching associated with dandruff.
  • to treat a skin condition known as pityriasis (tinea versicolor), a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs.

Resolve shampoo exerts Triple Action with its unique preparation-

  • Ketoconazole 2%: clears dandruff and scalp seborrheic dermatitis, controls itch and prevents relapse when used prophylactically.
  • Zinc Pyrithione 1%: exerts antiseborrheic and keratolytic action. It works by slowing the production of skin cells and sebum, which helps to reduce flakiness.
  • Glusol Powder: acts as conditioning agent to leave hair moisturized, manageable, shiny and sublimely soft.

 

Cerebro-vascular

Citicol®

Citicoline 500 mg Tablet
Citicoline is a brain chemical that occurs naturally in the body. As a medicine, it is taken by mouth as a supplement or given by IV or as a shot.

Indications:
Citicoline is used for Alzheimer's disease and other types of dementia, head trauma, cerebrovascular disease such as stroke, age-related memory loss, Parkinson's disease, attention deficit-hyperactive disorder (ADHD), and glaucoma.

BEXIMCO PHARMACEUTICALS LTD.

News Release

25th October 2011

Beximco Pharma introduces Dinovo

Leading drug manufacturer Beximco Pharmaceuticals Ltd (BPL) has introduced Dinovo®, a combination of Naproxen and Esomeprazole Magnesium, for the first time in Bangladesh. Dinovo® is indicated for the relief of signs and symptoms of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis without causing NSAID-associated gastric injury.

Though NSAIDs are effective against pain and inflammation, these can cause gastric injury and ulcer on long term use. Hence, PPIs are usually routinely prescribed with NSAIDs to protect against potential gastric injury. However, many patients may not get full benefit of protective PPI therapy as they forget to take the PPI or feel uncomfortable to maintain the timing of PPI intake.

Combination of naproxen and esomeprazole is an effective and well tolerated treatment option for osteoarthritis patients at risk of developing NSAID-associated gastric ulcers. A single tablet delivers both the proven pain relief of naproxen with the gastric ulcer risk reduction of esomeprazole in every dose of the medication.

Dinovo® is specially designed for ulcer risk reduction. Immediate-release esomeprazole is released first in the stomach and reduces gastric acid secretion by inhibiting the enzyme H+K+-ATPase – the acid pump and inhibits both basal and stimulated acid secretion. The release of esomeprazole is followed by the dissolution of naproxen in the small intestine. The enteric coating prevents the release of naproxen at pH <5, providing protection against possible local gastric toxicity of naproxen. After reaching intestine, naproxen is released and gets absorbed in blood to exert anti-inflammatory and analgesic action.

BEXIMCO PHARMACEUTICALS LTD.
New product launches in 2013

During January to September 2013 Beximco pharma has further extended its product line with 21 new products across therapeutic groups of Cardiovascular, Antibiotics, Antifungal, Vitamins & Mineral supplements, Pain management, Erectile Dysfunction (ED) and Anti-diabetics.

Oral Anti-Diabetics


Diapro® 30 MR
Gliclazide 30 mg Modified Release Tablet

Diapro® is an oral blood glucose lowering drug of the sulfonylurea class. Diapro® is used to treat patients with type 2 diabetes mellitus. The primary mechanism of action of Diapro® is lowering of blood glucose by stimulating the release of insulin from functioning pancreatic beta cells. In addition, expancreatic effects may also play vital role in the activity of Diapro®. Administration of Diapro® can lead to increase sensitivity of peripheral tissues to insulin

Cardiovascular


Metazine®MR
Trimetazidine Hydrochloride 35 mg Tablet

Metazine® MR is a Modified Release formulation of mg which is a unique anti-anginal and anti-ischemic agent that exerts anti-ischemic effects without inducing hemodynamic changes and improves the status of ischemic myocardium. Trimetazidine is indicated in adults as add-on therapy for the symptomatic treatment of patients with stable angina pectoris who are inadequately controlled by or intolerant to first-line anti-anginal therapies.

Metoprol®- XL
Metoprol 50 & 100 mg Tablet

Metoprolol succinate, is a beta1-selective (cardio selective) adrenoceptor blocking agent, for oral administration, available as extended release tablets. METOPROL-XL has been formulated to provide a controlled and predictable release of Metoprolol for once-daily administration. The tablets comprise a multiple unit system containing Metoprolol succinate in a multitude of controlled release pellets. Each pellet acts as a separate drug delivery unit and is designed to deliver Metoprolol continuously over the dosage interval.

Citicol®
Citicoline 500 mg/4ml IV/IM Injection

Citicol® is a psychostimulant/nootropic agent indicated for patients suffering from stroke, age-associated memory impairment (AAMI), head injury, cerebrovascular disorders (disease of the blood vessels supplying the brain). Citicoline is also indicated for cognitive support and support for nerves of the eye.

 Erectile Dysfunction


Adafil®
Tadalafil 10 mg Tablet

Adafil® contains Tadalafil which is a potent, selective, reversible inhibitor of cyclic Guanosine Monophosphate specific Phosphodiesterase type 5 (PDE5). Adafil® is indicated in erectile dysfunction (ED).

Antifibrinolytic


Tranexil
Tranexamic Acid 500 mg/5ml Injection

Tranexil® a antifibrinolytic agent is effective to reverse the effects of streptokinase or other fibrinolytic activity. It may be used for conditions in which bleeding control is required such as after surgery or injury, recurrent nosebleeds or abnormal vaginal bleeding.

Vitamins & Minerals Supplements


 Calorate®
Calcium Orotate 400 mg Tablet

Calorate is a calcium supplement with a functional amino acid chelating ligand - orotic acid. Orotic acid assists the transport of calcium through cellular membrane structures, thus facilitating the intracellular uptake of calcium, particularly in bone. Calcium Orotate also helps in the maintenance of healthy cartilage. Calorate® is used to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets.

Hemofix®
Ferrous ascorbate Tablet

Hemofix® tablet contains ferrous ascorbate 275 mg equivalent to elemental iron 33 mg. Ferrous ascorbate is a synthetic molecule of ascorbic acid and iron. Ascorbic acid plays an important role in the movement of plasma iron to storage depots in tissues. This molecule doesn’t dissociate on entering the GI tract due to the stable chelate of iron with ascorbate. Ascorbate is a reducing agent and prevents oxidation. Hence, it maintains iron in highly soluble ferrous form. All this factors contribute to the highest absorption of ferrous ascorbate. Hemofix® is indicated in the treatment of iron deficiency anemia

Hemofix® FZ tablet
Ferrous ascorbate +Folic acid+ Zinc

Hemofix® FZ is a film coated tablet containing ferrous ascorbate equivalent to elemental iron 48 mg, folic acid 0.5 mg & Zinc Sulfate Monohydrate 61.8 mg equivalent to elemental zinc 22.5 mg. It is indicated on prophylaxis of iron deficiency especially when an inadequate diet calls for supplementary zinc and iron during pregnancy and anemia

Jointec® Max
Glucosamine + Diacerin Tablet

Jointec® Max is a combination of Diacerein 50 mg and Glucosamine sulfate 750 mg tablet, which is indicated for the treatment of Osteoarthritis. Diacerein is a new antiinflammatory drug, developed specially for the treatment of Osteoarthritis. Glucosamine Sulfate is a naturally occurring chemical found in the human body

Pain management


Feburic®
Febuxostat 40 mg Tablet

Feburic® contains the active ingredient febuxostat, which is a type of medicine called a xanthine oxidase inhibitor. Febuxostat is used to treat gout.

Nervalin®
Pregabalin 50 & 75 mg Capsule

Nervalin is a modulator of voltage-gated calcium channels, designed to affect neurological transmission in multiple systems. It is specifically indicated for the treatment of neuropathic pain associated with spinal cord injury. It is also indicated for the treatment of neuropathic pain associated with diabetic peripheral neuropathy, for post herpetic neuralgia, for fibromyalgia, and as an adjunctive therapy for adults with partial onset seizures.

Voligel®
Diclofenac sodium 50 gm gel

Voligel® is the unique topical preparation of Diclofenac sodium, methyl salicylate & menthol. It gives instant relief from any kind of muscle & joint pain such as back ache, neck & shoulder pain, joint pain etc. The launching of Voligel® offers patients a new way to treat daily aches with outstanding safety.

Eye Irrigating Solution


Navsol® Irrigating Solution
Balanced Salt Solution

Navsol® Sterile Irrigating Solution is a sterile physiological balanced salt solution of Sodium Chloride (NaCl), Potassium Chloride (KCl), Calcium Chloride Dihydrate (CaCl2•2H2O), Magnesium Chloride Hexahydrate (MgCl2•6H2O), Sodium Acetate Trihydrate (C2H3NaO2•3H2O), and Sodium Citrate Dihydrate (C6H5Na3O7•2H2O). Navsol® is isotonic to the tissues of the eyes and is indicated as irrigation solution during various surgical procedures of the eyes, ears, nose and/or throat.

Antibiotics


Tyclav®
Amoxycillin + Clavulanic acid Tablet

Tyclav® (375 mg, 625 mg and 1 g tablet) is an antibacterial combination consisting of amoxicillin and the beta-lactamase inhibitor, clavulanate potassium. Amoxicillin is a semi-synthetic antibiotic with in vitro bactericidal activity against Gram-positive and Gram-negative bacteria. Clavulanic acid is a beta-lactam, structurally related to the penicillins, which possesses the ability to inactivate some beta-lactamase enzymes commonly found in microorganisms resistant to penicillins and cephalosporins.The formulation of amoxicillin and clavulanic acid in Tyclav protects amoxicillin from degradation by some beta-lactamase enzymes and extends the antibiotic spectrum of amoxicillin to include many bacteria normally resistant to amoxicillin.

Antifungal


Omastin® IV
Fluconazole 2mg/5ml

Omastin injection is used to treat serious fungal or yeast infections, such as vaginal candidiasis, oropharyngeal candidiasis (thrush, oral thrush), esophageal candidiasis (candida esophagitis), other candida infections (including urinary tract infections, peritonitis [inflammation of the lining of the abdomen or stomach], and infections that may occur in different parts of the body), or fungal (cryptococcal) meningitis

Osteoporosis


 Calorate Kit

1 tablet of Ibandronic Acid 150 mg+ 60 tablets of Calcium Orotate 400 mg Beximco Pharmaceuticals Ltd. (BPL) introduced Calorate® Kit for the first time in Bangladesh. Calorate® kit comprises 1 tablet of Ibandronic Acid 150 mg and 60 tablets of Calcium Orotate 400 mg, indicated for the treatment and prevention of osteoporosis. Osteoporosis is characterized by low bone mass and structural deterioration of bone tissue, leading to bone fragility and an increased risk of fractures of the hip, spine and wrist. Osteoporosis is a major cause of mortality and morbidity of post-menopausal women.

Ibandronic acid increases bone mineral density (BMD) and reduce the incidence of vertebral fractures. One tablet of Ibandronic acid 150 mg once monthly on the same date of each month is recommended.
To maximize clinical benefit of Ibandronic acid, two tablets of Calcium orotate 400 mg per day are usually recommended in divided dosage or as directed by physician.

BEXIMCO PHARMACEUTICALS LTD.

News Release

10th October 2011

Beximco Pharma introduces NapaDol

Leading drug manufacturer Beximco Pharmaceuticals Ltd (BPL) has introduced for the first time in Bangladesh, NapaDol; combination of Paracetamol & Tramadol for the treatment of moderate to severe pain.

Fixed dose combination of Paracetamol & Tramadol provides better pain relief than the individual molecules. Moreover, after surgery, tramadol inj. often prescribed to relieve post operative pain. But, injection generally given for short time. In this case this combination would be effective as maintenance therapy of post operative pain. Apart from this, paracetamol & tramadol combination shows excellent efficacy against painful osteoarthritis flare, traumatic pain & low back pain. Results of the published clinical literature suggest that Tramadol/Paracetamol, by reducing the incidence of adverse events, provides benefits for patients. Till the launching of NapaDol, Paracetamol & Tramadol were being used separately for the management of pain. Combination of Paracetamol & Tramadol provides dosage convenience to patient.